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Medically Reviewed On: September 12, 2003

Survival rates for breast cancer have improved steadily over the last decade, thanks to earlier detection and better treatments. The aim of therapy, particularly among women with early-stage breast cancer, is to not only eliminate the cancer, but to prevent it from coming back. Typically, treatment begins with the surgical removal of the tumor, and continues in an effort to stop rogue cancer cells that may have been left behind.

Treatment that is given after surgery specifically to prevent recurrence is called adjuvant therapy. Adjuvant therapies for breast cancer include radiation treatment, chemotherapy and hormonal therapy.

Below, Dr. Marisa Weiss, an oncologist and president and founder of breastcancer.org, a non-profit organization for women with breast cancer, discusses the role of adjuvant therapy and explains each type of treatment.

What is adjuvant therapy?
Adjuvant therapy is the treatment for early-stage breast cancer after surgery has been completed. Its role is to reduce the chance of recurrence. Adjuvant therapy can include radiation to the whole breast, and systemic treatments that include hormonal treatments and chemotherapy.

The primary goal of treatment for breast cancer is to treat the whole breast. That can be accomplished by removal of the whole breast, or mastectomy. Or it can be accomplished by breast preservation therapy, which involves removal of the lump.

In general, the plan for adjuvant therapy is established after all the information comes back from surgery. So that means adjuvant therapy could begin as soon as two weeks after surgery. But it can also start up to month after surgery is finished.

In that period of time, a woman needs to get opinions from the surgeon, from the medical oncologist, the radiation oncologist, as well as the pathologist and the radiologist so that the treatment plan is tailored to the woman's situation.

What does chemotherapy involve?
Chemotherapy is one option for reducing risk of recurrence. Generally, chemotherapy works by blocking the growth of cancer cells, keeping them from making new cells and preventing cancer cells from repairing themselves.

Chemotherapy may be an option for someone who has cancer that is large; that has lymph node involvement; that does not have hormone receptors; or that has features that indicate it may be an aggressive tumor. The doctor uses these different pieces of information to determine a woman's risk of having cancer elsewhere.

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